Central odontogenic fibroma (cof) is an uncommon odontogenic neoplasm derived from odontogenic ectomesenchyme, representing less than 1% of all odontogenic neoplasms. It occurs centrally within the jaw bones and manifests usually as an asymptomatic, slowly growing, hard, bony swelling, leading to cortical expansion and facial asymmetry., this article reports clinical, radiological and histological features of cof occurring in the left mandible of a 13 year old male with an emphasis on distinguishing this tumor from some other centrally occurring lesions with similar clinical presentation like myxofibroma and desmoplastic fibroma.

Key words:-central odontogenic fibroma, odontogenic tumors, mixed odontogenic tumors, central bone lesions, desmoplastic fibroma, myxofibroma