AbstractEpidural block is the procedure to block the nerve roots outside the dura. It is the method providing analgesia, reflex flaccidity to muscles, degree of hypotension and ischemia secondary to sympathetic blockade while allowing spontaneous respiration to continue relatively unimpaired. This study was done to observe the onset and duration of sensory and motor block and duration of postoperative analgesia. The study was conducted on 90 indoor patients of either sex belonging to ASA-I & ASA-II, aged 20-70 years scheduled for lower abdominal or lower limb surgery, were randomly allocated in 3 groups of 30 patients each. Group 1 received Epidural block with lignocaine and adrenaline 1.5%, Group 2- Epidural block with bupivacaine 0.375% and Group 3 received Epidural block with lignocaine and bupivacaine mixture in ratio of 1:1. Patients were premedicated with Atropine 0.6 mg, Midazolam 2mg and Pentazocine 30mg intravenously after the epidural block was achieved. They were monitored for pulse rate, respiratory rate, blood pressure, onset of sensory loss, motor paralysis and total duration of sensory and motor block. The onset of sensory (11.9±3.16mins) and motor block (13.2±2.1mins)was earliest in group I and duration of block (261±76mins) was longest in group II