Context: Post Cesarean section substantial postoperative discomfort and pain can be anticipated. Pain inadequately relieved is deleterious and lead to number of complications in the postoperative period.The analgesic regime needs to meet the goals of providing safe and effective analgesia with minimal side effects for the mother and child. We conducted this study to formulate post-operative pain management strategies regarding the use of non-opioid analgesics. Aim: This study was conducted with aim to comparethe analgesic efficacy of Tramadol and Diclofenacsodium as rectal suppository in post-operative cesarean section.Settings and Design:This study was a randomized, controlled trial, carried out at tertiary care centre in India.The sample size for this study was calculated to be 50 in each group. Methods and Material: Adult (19-30 years) American Society of Anesthesiologist grade-I and II posted for cesarean section were included in the study. Patients were randomized by simple randomization method to receive either rectal suppository of Tramadol (Supradol) 100 mg or Diclofenac (Justin) 100 mg. Suppository  was introduced immediately after the surgery before shifting the patients to postoperative ward. Pain measurement in the postoperative period was performed using Visual Analog Scale at 0, 2, 4, 6, 8, 10 hours. Statistical Analysis Used: All data on categorical variables were presented as frequencies and percentages. Chi square test was used to compare the frequencies and percentages.All the statistical analysis were carried out at 5% level of significance and p value <0.05 was considered significant. Chi square test was used to compare the frequencies and percentages. Results: Statistically significant differences between two groups in VAS score was seen at 4,6,8 and 10 hours after surgery.80.4% of cases among Tramadol group needed rescue analgesia at 8 hours and 98.2% at 10 hrs. among Diclofenacgroup Only 4.2 %cases needed rescue analgesia at 8 hrs and 6.3 % at 10 hours. Conclusion: Diclofenacsuppository has better analgesic effect as compared with Tramadol suppository on postoperative pain.