Aims and objective: To compare heamodynamic parameters, complication, recovery time and time of early extubation with sevoflurane and desflurane.

Materials and methods: This was prospective study conducted from January to December 2020 using sampling technique total 60 adult patient of American society of Anesthesiologist (ASA) Grade I, II, III. Age between 18–60 years of either male or female who were posted for Laproscopic appendicectomy under general anesthesia were selected for study after informed consent. All the patient were randomly allocated into one of two group using computer generated random number table. Group ‘S’ received induction with sevofluraneamd Group ‘D’ received induction with desflurane.

Result: Both group did not differ significantly in age, weight, sex, ASA grade. Heart rate was significantly higher in the sevoflurane group than in the desflurane group after intubation. Systolic blood pressure was significantly higher in the sevoflurane group. The Sevoflurane group showed higher time in spontaneous respiration, verbal commands following, ET removal time.

Conclusion: Desflurane provides faster recovery from anesthesia and better hemodynamic
stability introperative and post operative.