Background: Neck pain with cervical radiculopathy (CR), nowadays, is usually confronted in physiotherapy clinics and hospitals. The prevalence of trigger points is more in patients with CR. So many studies have been done on the treatment of CR as well as myofascial trigger points (MTrPs) so far, but none focuses on the treatment of trigger points in CR. Myofascial release (MFR) is considered to be effective in resolution of MTrPs. Objective: To compare the effect of MFR along with conventional physiotherapy and conventional physiotherapy alone in patients with myofascial trigger points in cervical radiculopathy. Methods: 30 patients will be randomized into two groups according to the inclusion criteria. Group A (experimental, n=15) will be given MFR along with conventional physiotherapy; Group B (control group, n = 15) will be given conventional physiotherapy alone. Intervention will be given for 3 weeks and then reassessment will be done for the efficacy of MFR on Neck disability index (NDI), pain intensity, pressure pain threshold (PPT) on upper trapezius and upper limb neurodynamic test for median nerve (ULNT 1). Data analysis and Result: Shapiro–wilk test will be used for normality distribution of data and accordingly wilcoxon test or paired t-test will be used within the group and independent ttest or Mann whitney U-test will be used in between the groups for data analysis. Results will be expressed as mean±standard deviation. Conclusion: This study will contribute towards evidence based practice and help in determining if MFR and conventional physiotherapy will be better than conventional physiotherapy alone in treatment of MTrps in patients with CR.