Introduction: Peptic ulcers are ulcers, occurring in any portion of the gastrointestinal tract (GIT), in which mucosa is bathed in hydrochloric acid (HCl) and gastric juice. Ulcers can develop in the esophagus, stomach or duodenum, at the margin of a gastroenterostomy, in the jejunum, and in association with a Meckel’s diverticulum containing ectopic gastric mucosa. Methodology: The study was conducted in the Department of Surgery, Basaveshwara Teaching and General Hospital, Gulbarga Karnataka during the period of  Nov. 2011 to Sep. 2013. The diagnosis of duodenal ulcer perforation was that established by the admitting surgeon, based on clinical features and supposed by radiological evidence and confined at operation. Results: The morbidity rate was 10.17% and the mortality rate was 11.67%. Conclusion: Wound infection was common post operative complications