Primary plasmacytomas are rare and not many cases have been reported in literature. These are characterized by solitary bony lesions, neoplastic plasma cells, less than 5 % plasma cells in the bone marrow, less than 2.0gm/dL monoclonal protein in serum and a negative Bence Jones test for urine. These primary plasmacytomas involving the skull base are rare, as compared to surface bones of the skull and only 4-5 cases have been reported. We report a primary plasmacytoma involving the skull base producing lower cranial nerve deficit and trigeminal neuralgia.

Keywords: plasmacytoma, primary, skull base, neuralgia.