Regression of herniated disc fragments with subsequent improvement in clinical symptoms has been reported in the lumbar and cervical spine. Such regressions in the thoracic spine are extremely rare. We report a 38-year-old thalassemia patient who had regression of a large calcified herniated thoracic disc causing cord compression, with subsequent herniation of a second calcified disc at a different level, and discuss the possible etiopathogenesis. This is the first such case reported in the thalessemia population.

Keywords: Calcification; Iron chelation; Regression; Thalessemia; Thoracic disc herniation.