Background: The present study is an attempt to evaluate the causes and clinical manifestations of febrile thrombocytopenia in pediatric age group. Method: A careful history was recorded with general physical examination and detailed systemic examination. This was followed by routine investigations which included complete blood count, total leucocyte count, renal function test, liver function test, PT and INR, urine routine, ECG, USG, X-ray chest were done wherever indicated. Conclusion: Early onset sepsis was found to be the most common etiology of febrile thrombocytopenia among pediatric age group. After fever, the most common clinical manifestation was chills and rigor; and icterus. Most common bleeding manifestation was petechiae commonly seen in cases with severe thrombocytopenia. The clinical presentation of such cases is mostly sufficient to diagnose the condition and start its management. Study Designed: Prospective Observational Study.

Keywords: Clinical; Manifestations; Thrombocytopenia; Children & Fever.