Background: Abnormal uterine bleeding (AUB) is the most commonand challenging problems presenting to gynaecologists now-a-days. Any bleeding pattern deviated from normal menstrual cycle results in AUB.

Aims and objectives: The present study was conducted to study the histopathological patterns of endometrium in patients presenting with AUB and to elucidate the causes of AUB in different age-groups.

Materials and Methods: 200 cases were analysed in Index Medical College Research centre and Hospital, Indore. The study was conducted after satisfying the specific inclusion and exclusion criteria. The specimens were routinely processed and H & E stained slides were studied. A statistical analysis between the age of presentation and specific endometrial finding was done using Chi-square test.

Result: The most common age group presenting with AUB was perimenopausal (40-50 years) with 107(53.7%) cases followed by reproductive (<40 years) age group with 83 (41.5%) cases. The most common histopathological pattern in perimenopausal patients was simple hyperplasia in 34 (31.78%) cases followed by proliferative phase in 29 (27.10%) cases. Overall proliferative phase was in 64 (32%) cases, simple hyperplasia in 53 (26.50%) cases, secretory phase in 46 (23%) cases, atrophic endometrium in 14(7%) cases, asynchronous endometrium in 9 (4.50%) cases, complex hyperplasia in 6 (3%) cases, endometrial polyp in 4 (2%) cases, endometrial carcinoma in 4 (2%) cases.

Conclusion: The study of histopathological pattern of endometrium in AUB cases is helpful to diagnose and properly manage the cases. There is an age specific association of endometrial findings.

Keywords: Abnormal Uterine Bleeding; H&E Stain & Histopathological Findings.