A non healing ulcer occurs due to variable conditions like diabetes mellitus, varicose ulcer, and arterial ulcer, badly crush injuries, etc. The management of non healing ulcer is quite difficult task to the doctor and a terrifying for the suffering patient even many options are available. In Ayurveda, these non healing ulcers can be correlated with Dushta Vrana which is difficult to heal. Sushruta mentioned many formulations for healing of Dushta Vrana among them Yashtimadhu Ghrita (Glycyrrhiza glabra L.) is one of the ghrita formulations. In this study, a male patient of 38 years, presented with a non healing ulcer at medial mallelous of right foot. The ulcer was developed due to post accidental wound debridement. The patient had taken treatment and local dressing with antiseptic from last one year without much improvement in wound. The routine laboratory investigations were within normal limit. The wound was treated with local application of Yashtimadhu Ghrita daily once followed by Manjisthadi Kwath (10 ml two times) and Rasayana Choorna (5 gm two times) orally. This case study showed wound healing activity Yashtimadhu Ghrita by local application.

Keywords: Dusta Vrana; Glycyrrhiza Glabra; Non Healing Ulcer; Yashtimadhu Ghrita; Wound.