Oral cavity is a major entrance for bodily entities. It has a high risk of getting infections, irritations, etc. Oral Submucosal Fibrosis (OSMF) is an Oral submucous fibrosis is a chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the submucosal tissues. This is called a disease of Indians. Because, it is most predominantly found in Indians and Indians living abroad. Exact etiology is unknown. The pathogenesis of the disease is not well established, believed to be multifactorial. No definite cure and management is available for OSMF. Only symptomatic relieving measures should be done. Use of topical anesthetics and analgesics alters the taste perception thus, impairs digestion and subsequent processes. Matsyaakshi is a drug with traditional values, available in all the seasons, throughout the India. It is rich in antioxidant betacarotene, Vitamin C and other essential chemicals. It is a traditional drug of choice for controlling the pain in oral cavity. This controls the pain in oral cavity rather than altering the taste perception and thus, does not interfere with the digestion. 

Keywords: OSMF (Oral Submucosal Fibrosis); Matsyaakshi; Anaesthesia.