Hypertrophic scars are a result of exuberant wound healing following skin injury and deposition of excess collagen. Despite the introduction of a wide variety of management protocols for hypertrophic scars, no definitive treatment has been established with optimal clinical results so far. Angiotensin II activation by angiotensinconverting enzyme (ACE) is a significant mediator in wound healing and collagen production. In this study we aim to evaluate the role of topical enalapril in hypertrophic scar treatment.