In the field of oncology, the understanding of the complex molecular mechanisms that transform a normal cell into an aberrant one with the dysregulation of alternative complementary pathways have led to a significant progress in the biomarker technology backed by clinical diagnostic tests.We have been now able to achieve extremely targeted treatment approach for each individual. In this article we have projected certain specific predictive biomarkers, their invaluable role in cancer Chemotherapy and companion diagnostic tests that are gaining increasing acceptance in the cancer clinics.

Keywords: Cancer Biomarkers; Targeted Therapy and Personalized Medicine.