Aim: To study the pattern of availability of life saving medicines for better patient care in intensive care unit and radiology department of tertiary care hospital. Design: Retrospective observational study in the past six years (2012-2018). Material and Methods: A team of researchers studied the pattern of availability of routine and life saving medicines in two intensive care units and radiology department of the hospital during the last six years and related it with the newer methods adopted to procure the same. The researchers studied the new and faster methods of procurement adopted in the hospital. The study focused on procurement of drugs for the past three years (2015- 2018) by newer methods and compared to older methods of procurement in the previous three years (2012-2015). The research took place at ten bedded trauma intensive care, seven-bedded First floor ICU and department of radiology for availability of routine and emergency medicines. Statistical Analysis: Categorical variables were presented in number and percentage. The researchers observed significant improvement in availability of life saving and routine medicines in the intensive care unit and radiology department. Results: The research showed satisfactory availability of life saving medicines in the two designated Intensive Care Units and radiology department due to adoption of new and faster methods of procurement in the past three years (2015-2018). Conclusion and Recommendation: Adequate training of staff regarding inventory management and implementation of Public Finance Management Systems led to better management of inventory in main store and concerned departments.