Background: Chest pain may be a symptom of a number of serious conditions and generally considered as a medical emergency. In ER the typical approach to chest pain involves ruling out the most dangerous cause and elimination or confirmation of the most serious cause, a diagnosis of the origin of the pain may be made.

Objective: To study clinical profile of patients presenting with chest pain in emergency department.

Method: This prospective observational study was performed on 71 patients who had presented with chest pain in emergency department of a tertiary care hospital in south India, Amrita Institute of Medical Sciences and Research Centre (Kochi).

Results: In all 71 patients included in the study, the cause of chest pain was reliably determined. There was 57 (95%) males and 14 (5%) females included in the study. The median values are as follows age group (60), Heart rate (74), Mean Arterial Pressure (100), Oxygen saturation (98), Respiratory rate (20), Temperature (98) and Random blood sugar (98).

Conclusions: In the 71 patients, the major cause of chest pain was cardiac in origin in 52 patients (73%) and remaining were non cardiac causes in 19 patients (27%). Among cardiac causes, ACS was found as the major cause of chest pain in 31 patients (43%) followed by other cardiac causes in 21 patients (30%).