Coronary angiography and catheterisation of the heart are most widely performed tests for the diagnosis and quantification of coronary artery diseases, identification of structural abnormalities of the heart (including valvular heart diseases), and hemodynamic status monitoring. There are very high risks and complications associated with these procedures that relate to the patient’s conditions and also, the skill and operational abilities of the operator. In this case report we see a very interesting case of fractured coronary guide wire retention in the heart, its migration to distant artery and later its retrieval through surgical approach.