AbstractMultiple sclerosis is a chronic autoimmune inflammatory disease characterized by axonal degeneration and demyelination of the central nervous system Isolated facial nerve palsy is commonly seen with Bell's palsy. However, it can be associated with a central lesion at the level of the ipsilateral facial nucleus or the facial nerve at the pons. Isolated cranial neuropathies are rarely seen with multiple sclerosis. Isolated facial nerve palsy due to multiple sclerosis is a rare scenario and can often get misdiagnosed and treated as Bell's palsy. The patient being reported is a 30-year-old female who developed isolated facial nerve palsy, which was initially treated as Bell's palsy. However, she was found to be knowncase of multiple sclerosis.