Over the years, discrimination based on race, gender, disability, sexual status, or gender identity has become more prominent. While organisations and groups are making efforts to end the discrimination, constitutions and lawmakers have to play a role in overcoming this injustice. This research argues that the various challenges that vulnerable individuals face include the idea that they are seen and treated as nuisances and threats to the national values, moral order, religious beliefs, and everyday notions of gender identity. Therefore, this research aims to explore the roles constitutions can play in alleviating the sufferings of victims of discrimination. The research method adopted is the doctrinal research, involving the analysis of existing literature on the topic and applying reasoning, as well as observation principles to deduce viable solutions to the injustice. Focus was placed on reports from United States of America and other foreign countries due to their robust literature on the subject matter. This study found that the explicit inclusion of the vulnerable individuals in the constitution may have a more significant impact in overcoming the injustice of discrimination against such group. This research recommends that constitutions provide explicitly for enforcement of the rights of everyone against all forms of discrimination undermining their gender identities.