The objective of this review article is to appraise the different infectious causes leading to congenital malformations in a fetus. Apart from being traumatic to the parents, repeat pregnancy losses or having a congenitally malformed baby,it is a great challenge to diagnose and suspect this causes to the physician Literature search in pubmed and google scholar revealed various aspects of this infections. The mode of transfer to the fetus and the degree of the fetal affection depends on various factors like the gestational age of attack of organisms,the virulence of the organisms and the inocullum of the organism. Infection with Rubella,cytomegalovirus, toxoplasma gondi are the main organisms which are associated with congenital malformations in the fetus.this can lead to either a lethal effect or a defective organogenesis in the fetus. This article aims to throw a light on the various infections,their ill effects and mode of transfer to the fetus. Evidence also supports the routes of infection and the gestational age of contracting the infection by the fetus and the factors which determine the outcome of pregnancy after the fetal infections.

Keywords: Rubella; CMV; Toxoplasmosis; Congenital malformations.