Introduction: Henoch-Schönlein purpura (HSP) is a small blood vessel vasculitis. The exact cause of the disease is unknown.

Case report: We reported a case of 40-year-old male who presented with the appearance of red macules on his extremities and face, along with vomiting, and pain in the abdomen and joints. The patient was initially diagnosed with Henoch-Schönlein purpura. Renal biopsy was suggestive of IgA nephropathy. One months later, he developed chronic diahorrea and duodenal biopsy shows strongyloides stercoralis (s. stercoralis) larvae and was treated with ivermectin following which his diahorrea subsided and later there was complete resolution of active urine sediments.

Conclusion: The time course of the disease and present knowledge concerning the pathogenic mechanisms of HSP suggest that s. stercoralis infection could have caused HSP in the presented patient, which was complicated by  nephritis.

Keywords: Henoch-Schönlein Purpura; Strongyloides Stercoralis.