Objective: To review various studies to identify Symptoms and suffering perceived by children at the end of life with cancer and the need of palliative care. Purpose of Review: Symptoms and suffering perceived by children at the end of life with cancer and identifying Paediatric palliative care, is an important aspect of care of children with life-threatening illnesses like cancer. We review recent publications with implications for care of these children. Data sources: he following database were searched i.e published research papers from different sources such as original journals, E journals and electronic database for example Pubmed, Medline, etc. The search of literature was archived by searching the references using several key words related to title and subject of the review. Literature was also archived from online Journal of American academy of pediatrics and general search portal such as Google search. Only articles written in English were included. The following keywords were used in combinations: symptoms of cancer, palliative care, end of life in children with cancer etc. Study Selection: studies were eligible if 1) studies conducted on perspective of parents on suffering of their children due to cancer only were included in this study ( there were many studies that evaluated the psychological and physical symptoms experienced by children with cancer at end of life were included), 2. The need of palliative therapy for children with end of life care was evaluated. 3. The studies were published in refereed journal were evaluated. However few studies were found that dealt with palliative care for children with cancer at end of their life’s, and all studies that evaluate palliative care were included. There were 10 studies met our criteria and were selected. Data Synthesis: Results of the studies were measured in terms physical and psychological symptoms and sufferings of children with at end of life, and palliative care provided as well as palliative care needed for children with cancer at end of life. All studies reviewed have shown that children with cancer is suffering with more physical and psychological symptoms apart from physical pain at end of their life that was not addressed properly by health care professional and need more palliative care. Conclusion: The result of research review support that the children with cancer suffer from fatigue, poor appetite, dyspnea, status epileptics and commonly suffering from pain, and psychological sufferings. these sufferings are not addressed adequately by health care professionals and need more palliative care and need additional systematic study, improved education and support for staff members, and continued development of more effective and compassionate delivery of pediatric palliative care. 

Keywords: Palliative Care; Cancer Children; Meta Analysis; End of Life Care.