End-stage renal disease is a chronic ailment that has a severe negative impact on the health related quality of life of patients.

Aim: of the study is to Assess the Disease Specific Quality of Life, Quality of Sleep and sleep hygiene among patients with ESRD undergoing Haemodialysis. Descriptive research design was used and it was done among 60 samples selected by purposive sampling technique at dialysis departments of selected hospitals, Thrissur. The study tools are a predesigned questionnaire; Kidney disease Quality of Life-36 item (KDQoL-36) survey tool; Sleep quality scale (SQS); and a structured statement. Descriptive (frequency, mean, percentage, standard deviation) and inferential (Karl Pearson correlation coefficient, Chi-square) statistics were used.

Result: Majority of the subjects responded to have an average disease specific QoL. About 70% of the subjects have good sleep quality and 83.3% did not practice basic sleep hygiene. The MCS subscales and Symptoms and problem subscales of KDQoL- 36 items had a significant positive correlation with quality of sleep at p≤0.05. Where as no significant correlation between sleep hygiene and the subscales of KDQoL-36 items survey tool and as well as between the quality of sleep. A significant association was found between MCS subscale with the education and type of family; Burden of Kidney disease subscale with education; Effect of kidney disease on their dailylife subscale with type of family; sleep hygiene with age and gender.

Conclusion: Health workers have a major role in improving the Disease specific Quality of Life, Quality of sleep and sleep hygiene among patients, to promote a positive treatment outcome.