Hospital nurses are exposed to various work-related factors that may be associated with an increased risk of developing different mental disorders. Empirical evidence on the prevalence and correlates of individual mental health problems such as stress, anxiety, and depression are widely reported, while a combined pattern of these conditions is unknown. This study aims to examine the co-occurrence of stress, anxiety, and depression among clinical nurses, and to explore socio-demographic characteristics of, and working conditions experienced by, nurses that may be associated with these three mental health conditions.