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Indian Journal of Forensic Medicine and Pathology

Volume  14, Issue 3, July – September 2021, Pages 347-354
 

Original Article

Frequency of Urinary Anomalies in Perinatal Autopsies

Pratima Manohar Pattar1, Sainath K Andola2, Asha Patil3, Suraj B4

1,3Assistant Professor, 4Associate Professor, Department of Pharmacology, ESIC Medical College & Hospital, Kalaburagi Karnataka 585105. 2Professor, Department of Pathology, M.R Medical College, Indian College of Pathologists, Kalaburagi, Karnataka 585105, India.

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DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.14321.4

Abstract

Background: Congenital anomalies of urinary system are common and are found in 3-4% of population, and 10% of terminations of pregnancies are attributable to lethal urinary anomalies. Although timely detection of nonlethal anomalies depends on many aspects, for instance equipment quality, sonologist experience and timing of the ultrasound examination. However, to confirm the findings and to attain definite diagnosis, a fetal autopsy after the termination of a pregnancy is of utmost important and is also crucial for genetic counseling.In view of this, the present study aimed to determine the frequency and to identify the types of the urinary anomalies in perinatal autopsies. Methods: This study includes 391 perinatal autopsies conducted prospectively from July 2016 to June 2018 at M. R. Medical College, Basaveshwar Teaching and General Hospital, Kalaburagi. After obtaining the consent from either parent, each fetus was examined as per the predetermined protocol which included ultrasound diagnosis, photographs, external and internal examination. Results: The gestational age ranged from 16weeks to 44weeks and the mean weight was 1123.96gm. Out of 391 cases urinary anomalies encountered in 19 cases )4.9%). Out of 19 cases, anomalies of renal parenchyma were seen in 15 cases )78.9%) and anomalies of pelvi-ureters and bladder was seen in 4 cases )21.1%). Three cases of urinary anomalies were associated with syndromes and 8 cases were associated with other system anomalies. Conclusion: The perinatal autopsy after termination of pregnancy is essential to confirm the ultrasound findings and to make a definitive diagnosis.

 

Keywords | Autopsy; Congenital anomalies; Ultrasonography; Urinary anomalies.
 


Corresponding Author : Suraj B: Associate Professor, Department of Pharmacology, ESIC Medical College & Hospital, Kalaburagi, Karnataka 585105, India.