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Indian Journal of Forensic Medicine and Pathology

Volume  13, Issue 1 (Special Issue), January-March 2020, Pages 225-228
 

Review Article

Methyl Alcohol Intoxication with Extensive Involvement of the Central Nervous System Shown By Magnetic Resonance Imaging

Demet Şeker

Assistant Professor, Department of Neurology, Giresun University Education and Research Hospital, Giresun, Turkey.

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DOI: http://dx.doi.org/10.21088/ijfmp.0974.3383.13120.28

Abstract

The focus of this study was to present methyl alcohol intoxication by citing clinical and laboratory, as well as radiological findings. A case of a 47-year-old man with a 20-year history of alcohol use disorder, brought to the emergency department in a coma. He had headache and blurred vision symptoms that started after drinking cologne and spirits. He had a Glasgow Coma Scale score of four. Increased anion gap metabolic acidosis was detected. Diffusion weighted imaging showed diffuse restriction regions in the subcortical white matter, cerebellar hemispheres, brain stem, bilateral optic nerve and putamen. He treated with hemodialyze, sodium bicarbonate, dextrose and ethanol infusion. However, the patient died on the seventh day. Bilateral putaminal necrosis is the most characteristic radiological finding, but white matter necrosis rarely reported in the literature. As in our case, such extensive involvement of the brain may be correlated with mortality in the acute period. 

Keywords: Methyl alcohol; Methanol; Intoxication; Magnetic resonance imaging.


Corresponding Author : Demet Şeker