The efficacy of Autologous Platelet Rich Plasma (APRP) for macrodactyly to reduce scarring post reduction in the bulk of the toe. Multiple applications of APRP have been identified in the field of scar management and wound outcomes previously. In our study APRP was utilised in a subject with left big toe macrodactyly to evaluate the efficacy and mechanism of action of a invasive body contouring intervention approach using APRP for scar management. Keyword: Autologous Platelet Rich Plasma (APRP); Macrodactyly; Scar reduction.