Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
International Physiology

Volume  7, Issue 1, January-April 2019, Pages 5-8
 

Original Article

Sympathetic Vascular Reactivity Has Ambiguous Relation with Age During Pregnancy

Reena Rani Verma1, Amit Kant Singh2, Shikha Seth3, Santosh Kumar Sant4, Anamika Singh5, Dheer Singh6, Nishu Bala7

1Junior Resident 2,4Professor 5Associate Professor, Departments of Physiology 3Professor, Obstetrics and Gynecology 6Professor, Departments of Anesthesia 7Medical Officer, Departments of Radiology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh 206130, India.

Choose an option to locate / access this Article:
90 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: DOI: https://dx.doi.org/10.21088/ip.2347.1506.7119.1

Abstract

 Background: Pregnancy is a physiological condition associated with adaptive changes in the maternal hemodynamics and cardiovascular system. Autonomic nervous system plays a central role in this adaptation to the various needs of pregnancy. One of the well-known complication, that occurs commonly during pregnancy is pregnancy induced hypertension (PIH)/preeclampsia (PE). Impairment of autonomic functions has been suggested as one of the cause of pregnancy induced hypertension. Vascular reactivity is defined as the responsiveness of a blood vessel to a specific stimulus. Blood pressure (BP) reactivity to the cold pressor test (CPT) has been suggested as a one of the predictor of hypertension. Materials and Methods: A total of 225 pregnant females with gestation age of 7-8 weeks as per the ultra-sonographic reports were recruited in the study and were divided into 3 groups 18-23 years (n=132), 24-29 years (n= 78) and 30-35 years (n=15). Observations and Results: The baseline SBP were 102.90 ± 11.95 mm Hg, 103.23 ±12.58 mm Hg, and 113.23 ± 12.53 mm Hg respectively in different age groups. The baseline DBP was 63.90 ± 9.20 mm Hg, 65.78 ± 10.92 mm Hg and 71.33 ± 9.17 mm Hg. It was observed that resting SBP and DBP increased with maternal age. The change in SBP and DBP during CPT was 12.02 ± 11.56 mm Hg and 12.12 ± 10.57 mm Hg in 18-23 years of age, 13.76 ± 16.22 mm Hg and 13.15 ± 14.99 mm Hg in 24-29 years of age, 12 ± 14.62 mm Hg in 30-35 years of age. This shows that there is more change in SBP and DBP till the age of 25-29 years which further decreased in 30 -35 years of age group. Conclusion: Thus there is an ambiguous relation of sympathetic vascular reactivity with age in pregnancy

Keywords: Pregnancy Induced Hypertension; Autonomic Nervous System; Vascular Reactivity; Cold Pressor Test.


Corresponding Author : Kant Singh