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International Physiology

Volume  6, Issue 3, Sep-Dec 2018, Pages 217-222
 

Original Article

Study of Cardiac Autonomic Activity using Heart Rate Variability in Normotensive Children of Hypertensive Patients

Deepika Kamath M.1, Niranjan Murthy H.L.2, Naveen S. Kotur3, Vijayanath V.4

1Assistant Professor, Department of Physiology, KS Hegde Medical Academy, Mangaluru, Karnataka 575018, India. 2,3Associate Professor, Department of Physiology, 4Professor & Head, Department of Forensic Medicime, ESIC­MC & PGIMSR, Bangalore, Karnataka 560010, India.

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DOI: DOI: https://dx.doi.org/10.21088/ip.2347.1506.6318.9

Abstract

  Introduction: Hypertension is an iceberg disease which is a risk factor for cardiovascular mortality. 45% of children with hypertensive parents have got a possibility of developing hypertension. HRV is a tool to identify autonomic dysfunction. Materials and Methods: 50 normotensive male cases with the parental history of hypertension and 50 age­matched healthy male controls were selected for the study. ECG was digitally recorded using BPL Cardiart 1087 ECG machine & Analog Digital Converter (NI­DAQ 7.5) and analyzed for SDNN, LF, HF, LF/HF ratio and E: I ratio. Results & Conclusion: SDNN, E: I ratio, HFnu were significantly reduced and LFnu & LF/HF ratio was significantly increased in cases. This indicated a reduced parasympathetic activity and increased sympathetic activity. 

Keywords: Heart Rate Variability; Cardiac Autonomic Activity; Hypertension; Sympathetic Overactivity; Parasympathetic Withdrawa


Corresponding Author : Niranjan Murthy H.L., Associate Professor, Department of Physiology, ESIC­MC & PGIMSR, Bengaluru, Karnataka 560010, India.