Obesity among children, adolescents has emerged as one of the most serious public health concerns in 21st century together can increase the risk of cardiovascular diseases, insulin resistance and dyslipidemia.

Aims: A comparative study between BMI & BP with CPT and Isometric handgrip dynamometer test for sympathetic activity.

Objective: To study the sympathetic activity with normal weight young adults and obese young adults.

Material Methods: A total of 100, of 50 normal weight and 50 obese medical and dental students in age group of 18-22 years. Each subjects Basal Blood pressure was recorded and evolution of sympathetic function test was done by using cold pressor test (CPT) and Isometric hand grip dynamometer test (IHD). Analysis of data was performed by SPSS 21.

Results: Sympathetic activity test values between obese non obese students significant differences was observed this indicates deranged sympathetic activity in obese.

Conclusion: Weight gain will cause sympathetic abnormality and prone to have hypertension & cardiovascular diseases.

Keywords: Cold Pressor Test; Isometric Handgrip Dynamometer; Obese.