The application of “negative pressure” has evolved to a cornerstone in the treatment of acute and chronic wounds in almost all specialties. Continuous Intermittent, and cyclic are the three types of Negative pressure Wound Therapy (NPWT). The cyclic NPWT system is similar to the intermittent mode in terms of using the same maximal sub-atmospheric pressure, but the pressure never reaches zero in the cyclic mode. The study assesses the role of cyclical Negative pressure wound therapy in adult burn wound healing.