Aim: To Study and Analyze the Effect of Perinatal Asphyxia on Blood Gas Analysis of Newborns. Background: Perinatal asphyxia, neonatal asphyxia, or birth asphyxia is the medical condition resulting from deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain. Hypoxic damage can occur to most of the infant’s organs (heart, lungs, liver, gut, kidneys), but brain damage is of most concern and perhaps the least likely to quickly or completely heal. Materials and Methods: This was a tertiary care teaching hospital based, prospective case control study conducted on normal full term and full term asphyxiated neonates delivered and admitted in the Neonatal Intensive Care Unit at Adichunchanagiri Institute of Medical Sciences, B.G. Nagara from December 2012 to May 2014. Results : In cord blood, the values for pH, base excess, and PO2 means were lower and the values for PCO2 were higher in the group of asphyxiated newborns as expected. All the differences were statistically significant. Conclusion: . Within the 18­24 hours of life, there were no differences between the two groups in terms of the values obtained through gas analysis, except for PO2, and base excess which was lower in the group of asphyxiated newborns.

Keywords: NewBorn; Blood Gas; Asphyxia; Umbilical Blood