The European Organization for Research and Treatment of Cancer- Quality of Life Questionnaire 30-Item Core Version (EORTC-QLQ-C30) is globally regarded as a gold-standard self-reported evaluation tool for Health-related quality of life (HRQoL) for use in cancer practice, education, research and administration. The objective of this review article was to address its applicability in various languages through studies on cross-cultural adaptation and translation-validation. There were 19 studies found on 13 languages (Chinese=4; Turkish=3; Taiwan Chinese=2; other ten languages=1 each), all of them reporting acceptable reliability, validity and responsiveness for the translated versions of EORTCQLQ-C30 for evaluating HRQoL in cancer patients in a variety of settings and situations. There is need for validating EORTC-QLQ-C30 questionnaire into Indian languages to facilitate its routine use in oncology and palliative care settings.

Keywords: Oncological evaluation; Quality of life;Psychooncology; EORTC-QLQ-C30.