Background: Newer 2 agonist agents have created a new chapter in faster and prolongation of neuraxial block and good postoperative analgesia. Intrathecal Dexmedetomidine studied in comparison with clonidine along with bupivacaine given intrathecaly for gynaecological surgeries. Materials & Method: patients belonging to the age group of 30­60 years posted for gynecological surgeries were taken for study. Patients were randomized into two groups, group D (30) received 15mg hyperbaric bubivacaine with 15 mcg Dexmedetomidine and group C received 15mg hyperbaric bubivacaine with 60mcg clonidine intrathecal. The quality of anaesthesia is evaluated by the onset of sensory and motor block, maximum height of sensory block, segmental regression of sensory block and total duration of motor block. Rescue analgesia required during the postoperative period was recorded. Result: Prolonged duration of sensory and motor block was feature of patients received dexmedetomidine. These patients are also hemodynamically stable with lack of sedation. Which is statistically significant (p < .001). The rescue analgesia time was 587 minutes in dexmedetomidine when compares to clonidine 408 minutes. Conclusion: Intrathecal dexmedetomidine causes good quality of anesthesia in the intraoperative period with prolonged postoperative analgesia with less requirement of rescue analgesia when compare to intrathecal clonidine.