Takotsubo cardiomyopathy (TTC), also transient apical ballooning if the left ventricle is a recently described and often underdiagnosed entity. The syndrome observed pre-dominantly in the postmenopausal women with signs very mimicking acute myocardial infarction. In most of the case reports emotional or physical stress factors has been identified as a trigger and perioperative stress has been suggested as the trigger in some cases. Outcome is favourable with the right treatment, though recurrences are possible. Here in this review the etiopathogenesis, diagnosis, prevention and management of this syndrome is elaborately described in terms of literature evidence.