Objective: To compare the analgesia, sedation and use of rescue analgesics after intra-peritoneal instillation of 0.2% plain ropivacaine versus 0.2% ropivacaine plus fentanyl in laparoscopic surgeries. Method: A double blind prospective randomized study was carried out in 100 ASA grade1 and grade 2 patients undergoing laparo-scopic surgeries. They were divided into 2 equal groups. One group (Group A) received plain ropivacaine 0.2% 2mg/kg while other group (Group B) received ropivaine 0.2% 2mg/kg plus fentanyl 2microgm/kg via intraperitoneal route before removal of trocar at the end of surgery. Visual analogue scale and Ramsay sedation score were used to assess postoperative pain and sedation at every 2 hour for first 12 hours, then 6 hourly till 24 hours and then 12 hourly for total of 48 h after surgery. The time of rescue analgesics was also compared between the two groups. Result: The demographic data was comparable between the two groups in terms of age, sex, weight and duration of surgery. The p value was significant between the two groups in terms of Visual analogue scale and Ramsay sedation score. Group B showed better postoperative pain relief and sedation as compared to group A. Also there was less need of rescue analgesia in group B in comparison to group A. Conclusion: intraperitoneal ropivacaine plus fentanyl gives better postoperative pain relief, sedation and less use of other rescue analgesics compared to plain ropivaine in laproscopic surgeries.

 

Keywords: Ropivacaine; Fentanyl; Laparoscopic Surgery;  Intraperitoneal Route