Background: Evidence informed practice relied upon evidence from systematic reviews and meta-analyses as the highest in the hierarchy in order to inform clinical practice decisions in foot and ankle rehabilitation in people with Diabetic peripheral neuropathic pain (DPNP) and Painful diabetic peripheral neuropathy (PDPN). Purpose:This study aimed to perform a systematic review and quantitative content analysis of systematic reviews on DPNP andPDPN. Materials and Methods:The extracted data about every included study included: journal, year of publication, number of authors, country of manuscript origin, goal of article (evaluation or intervention or both), subtypes of intervention (medical, surgical, or allied health), population characteristics (homogeneous or heterogeneous), and professional dimension. Results: There were 36 systematic reviews found, most of which were published from developed countries, in many scientific journals across the past 15 years, with lesser number of authors, with search strategy that utilized limited number of databases, included few studies, and they were predominantly on medical interventions. Conclusion: The few systematic reviews and meta-analyses on DPNP and PDPN provided evidence information for decision making towards evaluation and management of foot and ankle dysfunction in this population.

Key words: Evidence-based diabetes care; Diabetic peripheral neuropathic pain; Foot and ankle dysfunction; Painful diabetic peripheral neuropathy.