Background: Separation anxiety among children is common and normal.Children undergoing radiological imaging studies often require sedation to avoid panic episodes & severe anxiety for induction of Anaesthesia. It is important for the child to lie still during the scanning procedure & mostly we find it difficult for the children to keep still during a CT scan, which is usually about 10–15 minutes. This study aimed at comparing and evaluating the efficacy of use of intranasally administered Dexmedetomidine Vs intranasal midazolam for paediatric sedation undergoing diagnostic CT scan studies.

Methods: 100 paediatric patients within age group 1-10 years were divided into 2 groups of 50 patients each, Group I & II respectively, were given either intranasal Dexmedetomidine or Intranasal Midazolam. The depth of sedation was assessed by using University of Michigan sedation scale.

Results: This study concluded that Intranasal Dexmedetomidine is superior & more effective than Midazolam for pediatric sedation.