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Indian Journal of Diabetes and Endocrinology

Volume  2, Issue 1, January-June 2020, Pages 33-36
 

Review Article

Etiopathogenesis of Covid: 19 Infection in Patients with Underlying Diabetes

Asees Bajwa1 ,Sanjam Singh Chowdhary2

1PG, 2Research Scholar,

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Abstract

Type 2 Diabetes mellitus; HbA1c; Depression; Patient health questionnaire-9; Depression severity

Background: The pandemic due to coronavirus disease caused by SARS CoV-2 has caused significant morbidity and mortality across the globe. Underlying conditions such as hypertension, diabetes, cardiovascular diseases escalate the risk of various complications associated with covid-19 and leads to poorer prognosis. Therefore it is of prime importance to understand the cause of the severity of symptoms observed in patients with pre-existing type-2 Diabetes Mellitus. It is also imperative to decipher the chemical pathways involved in the causation of Diabetes which when intertwined with covid-19 leads to critical outcomes. Objective: The increasing per capita income has meant that the burden of non-communicable diseases now falls at India’s doorstep. So, we attempt to study diabetes in the backdrop of prevailing nCoV[1]2. According to World Health Organization (WHO), India had 69.2 million people living with diabetes in 2015. Thus it is crucial in a country like India with so many diabetic patients to explore the consequences of the pandemic on this cohort. Methods and Materials: We systematically searched the PubMed and Google scholar database for the published articleson diabetes and Covid-19till 11th July 2020. Conclusion: The relationship between Diabetes and Covid-19 and the likely chemical pathways involved in the pathophysiology have been elucidated. Based on the evidence that is available it is not possible to draw any certain conclusions. Though the present data that we have warranted further research to expound upon the poor prognosis observed in diabetic patients suffering from Covid-19.


Keywords : SARS CoV-2; chemical pathways; pathophysiology; Covid-19; type-2 Diabetes mellitus.
Corresponding Author : Asees Bajwa, Master of Public Health in Social Epidemiology from Tata Institute of Social Sciences, Mumbai aseesbajwa3@gmail.com