Thalassemia is an inherited autosomal recessive blood disorder. Which results in excessive destruction of Red blood cells and further leads to anemia. Thalassemia’sare prevalent World wide with 16,800 death and 4,39,000 severe cases in 2015. According to 2017 data 80 million are carriers of beta thalassemia, Beta thalassemia is more common in children. Thalassemia is caused by variant or missing genes that affects how the body make hemoglobin. Which people having thalassemia Make less hemoglobin and fewer Circulating red blood cells than normal results in mild or severe anemia.