Context: Introduction: In the current study, an attempt was made to determine the safe zone for the limited carpal tunnel incision in case of carpal tunnel syndrome, in order to avoid injuries to the median nerve, by measuring the distance of median nerve from radial styloid process. Aims: To determine the safe zone of the median nerve (during surgical procedures for treating carpal tunnel syndrome) using various measurements. Settings and Design: Descriptive study. Methods and Material: 23 upper limbs, both right (11) and left (12), obtained from embalmed cadavers formed the material for the current study. Measurements of Median Nerve (MN) diameter, its distance from Radial Styloid Process (RSP) and Medial Most Point of Ulna (MMPU) were taken. Statistical Analysis used: Mean and range. Results: A distance greater than 64.57% from RSP, of the distance between RSP and MMPU, according to our study, will be useful for surgeons in order to avoid damage to median nerve. Conclusions: The safe zone for surgical procedures in treating carpal tunnel syndrome, in order to avoid damage to the median nerve is a distance greater than 64.57% of the distance between RSP and MMPU.

Keywords: Median Nerve; Carpal Tunnel Syndrome; Flexor Retinaculum.