AbstractBackground: Sinoatrial Nodal artery is an artery which supplies the Sinoatrial node, the natural pacemaker center of the heart, usually a branch of right coronary artery but also from left coronary artery in variable percentage in different population. Aim: The aim of the study was To establish anatomical origin of sinoatrial Nodal artery , from Right coronary artery or left coronary artery in Indian human cadavers.To observe relation of Sinuatrial nodal artery to the root of Superior Vena cava Materials and Methods: The study was carried out on 64 formalin fixed Adult Human Cadaveric Heart Specimens of Indian population obtained from department of Anatomy, Sridevi Medical College, Tumkur and Adichunchanagiri Institute of Medical Sciences B. G. Nagara, Karnataka, India. Specimens with gross congenital anomalies were excluded from the study. The coronary arteries were dissected for the origin of sinoatrial Nodal artery. Results: Out of total 64 cases studied, sinoatrial nodal artery was originating from right coronary artery in 34 (53.12 %) hearts, from left coronary artery in 17 (26.56 %) while in remaining 13 (20.31) hearts SA nodal artery was arising from both right and left coronary arteries. When it is arising from left coronary artery it is a branch of left circumflex artery rather than the main trunk.