Context: As human brain ages, characteristic structural changes occur that are considered to be normal. Knowledge of age related changes is important before analysing the abnormal findings. As age advances there is regression of brain tissue and thus ventricles size enlarges.

Aims: To analyse the morphometric measurements of lateral ventricles of the brain in different age group in both genders. Material and Methods: The study was done from Feb 2009 to July 2010. Data was collected from the CT scans Dept of Radiology Mysore Medical College & Research Institute. 200 normal CT scans (100 male, 100 female) in the age group of 10–80 yrs were collected.

Results: Right frontal horn measures 28.8 ± 2.5 in youngest and 30.3 ± 2.5 in oldest group. Right body part measures 47.9 ± 2.9 in youngest and 49.0 ± 1.9 in oldest group. Posterior horn measures 26.2 ± 1.9 in youngest age group and 26.0 ± 1.4 in oldest age group. Inferior horns could not be visible in few scans and were taken wherever possible as transverse diameter (TD) and vertical diameter (VD). All the measurements were found to be more in age group > 60 yrs compared to younger age group. Statistical methods: Data was analysed by using SPSS 2004 version, Standard Deviation and Independent ‘t’ test, analysis of variant and P – value.

Conclusion: Advances in CT imaging helps us to understand the normal structure and function of brain. The present study has shown increase in ventricular measurements as age advances.