A non-experimental descriptive study to assess the knowledge regarding covid-19 and it’s prevention among adolescent girls in selected colleges, Hyderabad. The objectives for the study are to assess the knowledge about covid-19 among adolescents, to assess the knowledge about its prevention among adolescents. A structured questionnaire was used to collect the data from the adolescent girls to assess the knowledge. Simple random sampling technique was used for the selection of sample. Total sample size for the study was 60. The results of the study is Majority of the adolescents 41 were having average knowledge, whereas 18 demonstrated above average knowledge and 1 had below average knowledge.