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International Journal of Forensic Science

Volume  5, Issue 1, January-June 2022, Pages 21-25
 

Original Article

Advantage of a SupplementaryX-STRs“Investigator Argus X-12 QS” PCR Kit in Solving a Paternity Case with one Mismatch on D21S11 Locus

Kunwar Veer Vikram Srivastav1, Rajesh Kumar2, Neha Gupta3, Kapil Kumar Gupta4, Vishwajeet Mishra5, Ankit

1,4,5,6Forensic Scientific Assistant, 2Assistant Director, DNA Division, State Forensic Science Laboratory, Rajasthan, Jaipur 302016, India, 3Assistant Professor, Guru Ghasidas University, Bilaspur, Chhattisgarh, 495009, India.

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Abstract

Genetic markers are very frequently used in human identification of paternity, maternity, and kinship cases. Establishing the kin relationships between a child and his biological father or biological mother involves many statical facts. DNA fingerprinting technology has been proven a useful tool worldwide to solve the crime. Before the discovery of DNA fingerprinting technology, other technologies such as dactyloscopy, anthropology, odontology, and medico-legal examinations were used for identification of human remains. These technologies provide limited information in comparison to DNA finger printing which provides the genetic information of the unknown human remains. The human remains may be soft tissue, bones, teeth, or hairs from which the genetic information can be extracted from these wide variety of biological materials. In conditions where the biological material mainly soft tissue is degraded due to climatic conditions, presence of scavengers, and rate of bacterial growth but skeletal remains (bone and teeth) are found intact in such situations. In these circumstances, hard tissues have been observed as the most suitable source for forensic application. In this study, we present a paternity testing case of a Very Rare Mutating Marker D21S11 between father and child. The average mutational rate of the D21S11 marker is estimated at 0.19%.


Corresponding Author : Kunwar Veer Vikram Srivastav,