Background: Testicular self-examination is the regular inspection and palpation of the testicles in order to detect any changes which might indicate testicular disease. Lack of knowledge of testicular cancer and Testicular self-examination (TSE) is a major problem in early detection and screening. Adolescent and young adult males must be taught to perform TSE as a normal routine health promotion activity. Training may ideally start at home and continue in schools and the workplace. Objectives: 1) Assess the knowledge regarding testicular self examination among male undergraduate students. 2) Evaluate the effectiveness of planned teaching on knowledge regarding testicular self examination among male undergraduate students. 3) Associate post test knowledge score with selected demographic variables. Materials & methods: A non experimental study one group pretest and post test design with structured knowledge questionnaire. Nonprobability purposive sampling technique was used. Sample size was 60. This study was conducted in higher secondary school in Seloo. Results: The pre test findings shows that 30% of the undergraduate students in pretest had poor level of knowledge score, 61.67% had average knowledge, 8.33% and in post test 25% had good level of knowledge score and 75% of the undergraduate students in post test had excellent level of knowledge score, thus it indicate that after post test the knowledge score was increased. Conclusion: the main aim of the study was to assess the effectiveness of planned teaching regarding regarding testicular self examination among male undergraduate students. After post test, the male undergraduate students had very good knowledge regarding testicular self examination. It was found that the planned teaching was effective.