Introduction: This paper presents relationship of school and sexual behaviour of adolescent. Context: Adolescent are the group where physical and psychological changes occur. Adolescents are the most susceptible group which faces challenges from society and educational institutions for which they are neither prepared nor they know how to address the problem. Aims: To investigate the cross-sectional relationship between Nature of school and Sexual behaviour of adolescent. Settings and Design: In this study, we have queried various controlled personal and sexual questions to 250 students of age 15-18 yrs. Methods and Material: This study gathered questionnaire based information from students of different types of schools of Ranchi suburb, Jharkhand, India. A total of 56 boys (37.34%) were from boys school and almost double of that were form co-ed schools (i.e. 94 (62.67%)). Based on the nature of school male participants were examined for selected sexual questions (Fig. 1). A total of 42 girls (42%) were from girls school and slightly higher than that were form co-ed schools (i.e. 58 (58%)). Based on the nature of school girl participants were examined for selected sexual questions (Fig. 1). Statistical analysis used: Parameters against which sexual questionnaire was examined are as follows: Nature and syllabus of School. The sample will be described in relation to the independent variables, stratified for nature and syllabus of school. Results: For sexual questionnaire (Have you noticed any bodily changes in yourself that you do not understand?) answers were taken in ‘YES’ and ‘NO’. A total of 7.14% male participant from boys school said ‘YES’ (i.e. they do not completely understand pubertal changes in themselves). Likewise, 9.58% of coed school students responded with a ‘YES’. Whereas, a total of 92.86% and 90.43% students from boys school and co-ed school responded ‘NO’ (i.e. they do completely understand pubertal changes in themselves), respectively. For sexual questionnaire (How do you feel when you see sexual content on television and/or online resource?), was provided with options such as, 1) disgusted 2) funny and 3) aroused. A total of 25% students from boys school said that they were ‘disgusted’ whereas, 47.88% students from co-ed schools said that they get ‘disgusted’ when they see sexual content on various media. Almost, 16% students from both boy’s school and co-ed schools said they found sexual contents on television and internet as ‘funny’. Interestingly, 58.93% students from boy’s school said they got ‘aroused’ by viewing sexual content on television and internet. Whereas, 34.05% students from coed school said they get aroused by viewing sexual content on television and internet. Conclusions: We confirm that adolescents from girls only school were more sexually educated and were least likely to be indulged in any reproductive health problems. Whereas, boys from co-ed schools were least likely to be indulged in any reproductive health problems. Children who are comfortable with their parents are least likely to be involved in criminal activity.