Health is the precious possession of all human being as it is an asset for an individual and community as well. Today health is recognized as a fundamental right of human being. Nowadays the major health problems in India are more in rural as well as urban areas. In rural areas mosquito borne disease are more due to unhygienic practices. Mosquito are the most important vectors of human infectious disease like malaria, Dengue, Filaria and Chikungunya. This mosquito came more human suffering than any other organism. Over one million people die from mosquito-borne disease every year. Today, dengue fever is considered one of the most important arthropod-borne viral diseases in humans in terms of morbidity and mortality. So researcher felt that is vital that children’s should possess knowledge on some vector born diseases especially dengue fever and its prevention. The research approach adopted in the present study was evaluative approach, and research design was one group pre test and post test design which belongs to pre-experimental design. Purposive Non random sampling technique was used to select the school as well as the sample. The sample size was of 60 children’s of aged between 10 to 18 years. Data were collected by using structured interview schedule and structured teaching programme was intervened, again after a gap of seven days post test was conducted with the same tool. Result showed that the pre test mean score was 14.03 (S.D =4.190) and in post test it was 22.80 (S.D =1.538) which indicated an improvement in the knowledge level of the respondents after structured teaching programme.