Health of the children has been considered as the vital importance to all societies because children are the future resources of mankind. Children are future citizens of our country. Statement of Problem: A descriptive study to assess the knowledge regarding management of fever among mothers of under five children in Amala institute of medical sciences & Research center, Thrissur. Objectives: To assess the knowledge of mothers of under-five regarding fever management, To find out association between level of knowledge and selected demographic variables, To prepare an information leaflet on fever management. The research approach adopted for this study is non experimental quantitative approach. The research design selected for this study is descriptive design. Population in this study consisted of mothers having children below five years of age sample in this study consisted of 50 mothers of under five children who were admitted in pediatric wards and OPD of Amala Institute of Medical Sciences. Convenient sampling was adopted for the study. Results: 2% of mothers were found to have very good knowledge. 27% of mothers having good knowledge. 21% of mothers having average knowledge. From the findings, it is found that there are association with income and usage of thermometer and knowledge of mothers. No association with selected demographic variables such as age, birth order, type of family. Nurse educators should continuously update their knowledge with latest research findings and provide health education programmes to mothers.