Context: The Super oxidized solution is a new concept of wound management. It has anti inflammatory effect that damage single cell organism not multicellular organism, therefore host tissues are spared.

Aims: To study the efficacy of topical SOS in Diabetic ulcers to observed Wound size, Time for appearance of healthy granulation tissue, Wound disinfection, Duration of hospital stay.

Settings and Design: Prospective, cohort & single centred, experimental study.

Methods and Material: 100 cases divided in to two groups for comparison between topical SOS and PI dressing for lower limb diabetic 
ulcers.

Statistical analysis used: p values, student t test. 

Results: in SOS and PI group patients wound assessments done on day 1,9,15 and 21 days and various wound outcome variables were compared. Patients were in the age group of 51-60 years and 68% were male. There was rapid decrease in wound size in SOS group compared to PI group at day 21, and earlier appearance of granulation tissue in SOS group. Resolution of peri wound erythema and peri wound edema was earlier in SOS group compared to PI Group. There was shorter duration of hospital stay, earlier wound disinfection and more number of patients who underwent skin grafting before 21 days in SOS group.

Conclusions: SOS with its moistening effects and cost effectiveness is safe, has faster response in wound healing and gives better efficacy as compared to the traditional Povidone Iodine solution for use as a topical / irrigant solution in wound care and in management of lower limb diabetic ulcers..

Keywords: Wound Debridement; Diabetic Foot; Super Oxide Solution.